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CD223 (LAG-3) Mouse anti-Human, Super Bright 436, Clone: 3DS223H, eBioscience™

Mouse Monoclonal Antibody

Brand:  Invitrogen 62-2239-41

Additional Details : Weight : 0.01000kg

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Product Code. 15855523

  • 1056.00 DKK / Pack of 25


Estimated Shipment date
from Supplier 28-05-2019
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Description

Description

Please make sure that your instrument is capable of detecting this fluorochrome. When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Staining Buffer (cat. SB-4400) to minimize any non-specific polymer interactions. Excitation: 405 nm; Emission: 436 nm; Laser: Violet Laser LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).
Specifications

Specifications

CD223 (LAG-3)
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
P18627
Lymphocyte Activation Gene-3
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
3DS223H
Super Bright 436
LAG3
Liquid
LAG3
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3902
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