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CD16 Mouse anti-Human, Super Bright 436, Clone: eBioCB16 (CB16), eBioscience™

Mouse Monoclonal Antibody

Brand:  Invitrogen 62-0168-42

Additional Details : Weight : 0.01000kg

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Product Code. 15865483

  • 2140.00 DKK / Pack of 100


Estimated Shipment date
from Supplier 05-06-2019
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Description

Description

Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm. We recommend using a 450/50 bandpass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome. When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Staining Buffer (Product No. SB-4400) to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information. Excitation: 405 nm; Emission: 436 nm; Laser: Violet Laser CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.
Specifications

Specifications

CD16
Monoclonal
5 μL/Test
PBS with BSA and 0.09% sodium azide; pH 7.2
O75015, P08637
CD16; CD16A; CD16B; FCG3; FCGR3; FCGR3A; FCGR3B;
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
eBioCB16 (CB16)
Super Bright 436
FCGR3A
Liquid
FCGR3A, FCGR3B
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
2214, 2215
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