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CD16 Monoclonal Antibody (eBioCB16 (CB16)), Super Bright™ 436, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
1126.00 DKK - 2575.00 DKK
Specifications
Antigen | CD16 |
---|---|
Clone | eBioCB16 (CB16) |
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15865483
|
Affymetrix eBioscience
62-0168-42 |
100 Tests |
2575.00 DKK
Pack of 100 |
In Stock Log in to see stock. |
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15855483
|
Affymetrix eBioscience
62-0168-41 |
25 Tests |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The eBioCB16 monoclonal antibody recognizes CD16 (Fc gammaRIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80 kDa. CD16 is represented by two similar genes, CD16A (Fc gammaRIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fc gammaRIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation. Applications Reported: This 0168 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 0168 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
CD16 Monoclonal antibody specifically detects CD16 in Human samples. It is validated for Flow Cytometry.Specifications
CD16 | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
2214, 2215 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
eBioCB16 (CB16) | |
Flow Cytometry | |
Super Bright 436 | |
Mouse | |
Human | |
FCGR3A, FCGR3B | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
FCGR3A |