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CD137 (4-1BB) Monoclonal Antibody (4B4 (4B4-1)), PE-Cyanine7, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
2960.00 DKK
Specifications
Antigen | CD137 (4-1BB) |
---|---|
Clone | 4B4 (4B4-1) |
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15805373
|
Affymetrix eBioscience
25-1379-42 |
100 Tests |
2960.00 DKK
Pack of 100 |
In Stock Log in to see stock. |
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Description
Description: This 4B4 (4B4-1) monoclonal antibody reacts with human CD137 (also known as 4-1BB or TNFRSF9), which is an inducible member of the TNFR family of costimulatory molecules expressed on T cells, natural killer cells, dendritic cells, granulocytes, and mast cells. Involved in recruiting TNFR-associated factors (TRAF) 1 and 2, CD137 signaling plays a role in T cell activation, maintaining the survival of activated and CD8 memory T cells, as well as suppressing myelopoiesis and dendritic cell development. Stimulation of this receptor has also been shown to promote expansion of CD4+CD25+ T regulatory cells i{ex vivoi}. The ligand for CD137, 4-1BBL, is found on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. Applications Reported: This 4B4 (4B4-1) antibody has been reported for use in flow cytometric analysis. Applications Tested: This 4B4 (4B4-1) antibody has been tested by flow cytometric analysis on two-day Con A-stimulated normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Light sensitivity: This tandem dye is sensitive to photo-induced oxidation.
CD137 (4-1BB) Monoclonal antibody specifically detects CD137 (4-1BB) in Human samples. It is validated for Flow Cytometry.Specifications
CD137 (4-1BB) | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
Q07011 | |
TNFRSF9 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
TNFRSF9 |
4B4 (4B4-1) | |
Flow Cytometry | |
PE-Cyanine7 | |
Mouse | |
Human | |
3604 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |