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CD103 (Integrin alpha E) Mouse anti-Human, APC, Clone: B-Ly7, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-1038-42

Additional Details : Weight : 0.23750kg

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Product Code. 15507986

  • 1798.00 DKK / 100 tests

In stock, ready to ship: 2

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Description

Description

Description: The B-Ly7 monoclonal antibody reacts with human CD103, the alpha E integrin. CD103 non-covalently associates with integrin beta 7. CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias. In vitro stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen, E-cadherin, binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium. Applications Reported: This B-Ly7 antibody has been reported for use in flow cytometric analysis. Applications Tested: This B-Ly7 antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

The CD103 antigen is a 160-130-105 kDa molecule which is expressed on mucosa-associated T lymphocytes and activated cells and on subet of TGF beta -1 cells. This human intra epithelial lymphocyte marker is the E integrin chain associated with the b7 subunit. CD103 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes. CD103 is expressed by 0.5 to 2% of resting lymphocytes in peripheral blood and lymphoid organs.
Specifications

Specifications

CD103 (Integrin alpha E)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P38570
ITGAE, HUMINAE
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
B-Ly7
APC
ITGAE
Liquid
ITGAE
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3682
Videos
SDS
Documents

For Research Use Only.