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CCT128930, MedChemExpress

Artikelnummer. 16496136
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100mg
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Artikelnummer. 16496136 Leverandør Medchem Express Leverandørnr. HY13260

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Beskrivelse

MedChemExpress CCT128930 is a ATP-competitive and selective inhibitor of AKT (IC50=6 nM for AKT2). CCT128930 has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). Antitumor activity.

CCT128930 is a ATP-competitive and selective inhibitor of AKT (IC50=6 nM for AKT2). CCT128930 has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). Antitumor activity.

Tekniske data

Kemisk navn eller materiale CCT128930
CAS 885499-61-6
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C18H20ClN5
Mængde 100 mg
Opløselighedsinformation DMSO : 33.33 mg/mL (97.50 mM; ultrasonic and warming and heat to 60°C)
SMIL ClC1=CC=C(C=C1)CC2(CCN(CC2)C3=NC=NC4=C3C=CN4)N
Molekylvægt (g/mol) 341.84
Formel vægt 341.84
Procent renhed 98.07%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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