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CCR6 inhibitor 1, MedChemExpress

Artikelnummer. 16465516
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10 mg
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Pakningsstørrelse:
50mg
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Artikelnummer. 16465516 Leverandør Medchem Express Leverandørnr. HY112701

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Beskrivelse

MedChemExpress CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer.

CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer.

Tekniske data

Kemisk navn eller materiale CCR6 inhibitor 1
CAS 2437547-04-9
Farve White
Renhedsgrad noter Research
Molekylær formel C24H23F3N4O3S
Mængde 100 mg
Opløselighedsinformation DMSO : ≥ 125 mg/mL (247.76 mM)
SMIL O=S([C@H](CC1)CC[C@@H]1NC2=NC=C(C(F)(F)F)C=C2)(C3=CC=C(C4=CC=NC(C(N)=O)=C4)C=C3)=O
Molekylvægt (g/mol) 504.52
Formel vægt 504.52
Procent renhed 99.87%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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