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Invitrogen™ Cathelicidin Polyclonal Antibody
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Artikelnummer. 12838692
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Mængde:
100 μg
Pakningsstørrelse:
100µg
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12838692 100 μg 100µg
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Artikelnummer. 12838692 Leverandør Invitrogen™ Leverandørnr. PA520513

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Beskrivelse

Rabbit Polyclonal Antibody

A suggested positive control is human spleen tissue lysate. PA5-20513 can be used with blocking peptide PEP-0633. The immunogen is located within amino acids 50 - 100 of Cathelicidin.

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
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Tekniske data

Antigen Cathelicidin
Applikationer Immunohistochemistry, Western Blot, Immunocytochemistry
Klassifikation Polyclonal
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering PBS with 0.02% sodium azide
Gene CAMP
Genadgangsnr. P49913
Gene Alias 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
Gensymboler CAMP
Værtsarter Rabbit
Immunogen A 17 amino acid synthetic peptide near the center of the human Cathelicidin.
Oprensningsmetode Antigen affinity chromatography
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 820
Målarter Human
Indhold og opbevaring 4°C, do not freeze
Produkttype Antibody
Form Liquid
Isotype IgG
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