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Invitrogen™ Cathelicidin Polyclonal Antibody
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Artikelnummer. 17731784
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100 μL
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17731784 100 μL
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Artikelnummer. 17731784 Leverandør Invitrogen™ Leverandørnr. PA5120383

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Beskrivelse

Rabbit Polyclonal Antibody

Positive test controls include: MCF7, A-549, PC-3, SP2/0, mouse testis, mouse spleen. The target is usually found in the following locations: Secreted. Immunogen sequence: NKRFALLGDF FRKSKEKIGK EFKRIVQRIK DFLRNLVPR.

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Cathelicidin
Applikationer ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Klassifikation Polyclonal
Koncentration 2.7 mg/mL
Konjugeret Unconjugated
Formulering PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene CAMP
Genadgangsnr. P49913
Gene Alias 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
Gensymboler CAMP
Værtsarter Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 132-170 of human CAMP (NP_004336.3).
Oprensningsmetode Affinity Chromatography
Mængde 100 μL
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 316010, 820
Målarter Human, Rat
Indhold og opbevaring -20°C, Avoid Freeze/Thaw Cycles
Produkttype Antibody
Form Liquid
Isotype IgG
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