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Invitrogen™ Cathelicidin Polyclonal Antibody
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Artikelnummer. 16678924
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Mængde:
100 μL
Pakningsstørrelse:
100µL
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16678924 100 μL 100µL
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Artikelnummer. 16678924 Leverandør Invitrogen™ Leverandørnr. PA5102453

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Beskrivelse

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Cathelicidin.

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
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Tekniske data

Antigen Cathelicidin
Applikationer Immunohistochemistry (Paraffin), Western Blot
Klassifikation Polyclonal
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CAMP
Genadgangsnr. P49913, P51437
Gene Alias 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
Gensymboler CAMP
Værtsarter Rabbit
Immunogen A synthesized peptide derived from human CAMP(Accession P49913), corresponding to amino acid residues I43-S93.
Oprensningsmetode Affinity Chromatography
Mængde 100 μL
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 12796, 820
Målarter Human, Mouse
Indhold og opbevaring -20°C
Produkttype Antibody
Form Liquid
Isotype IgG
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