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Invitrogen™ Cathelicidin Monoclonal Antibody (H7), FITC
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Artikelnummer. 17860226
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Mængde:
50 μg
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17860226 50 μg
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Artikelnummer. 17860226 Leverandør Invitrogen™ Leverandørnr. MA546584

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Description

Mouse Monoclonal Antibody

Predicted molecular weight: 19 kDa.

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cathelicidin
Applikationer Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry
Klassifikation Monoclonal
Klon H7
Koncentration 1 mg/mL
Konjugeret FITC
Formulering PBS with 0.09% sodium azide
Gene CAMP
Genadgangsnr. P49913
Gene Alias 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
Gensymboler CAMP
Værtsarter Mouse
Immunogen Partially purified human neutrophil membrane proteins (heparin Ultrogellectin affinity purification fractions in octyl glucoside).
Oprensningsmetode Protein G
Mængde 50 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 820
Målarter Human
Indhold og opbevaring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Produkttype Antibody
Form Liquid
Isotype IgG1
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