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Invitrogen™ Cathelicidin Monoclonal Antibody (C2), Invitrogen™
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Artikelnummer. 17694366
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100 μL
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17694366 100 μL
17604376 20 μL
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Artikelnummer. 17694366 Leverandør Invitrogen™ Leverandørnr. MA543915

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Beskrivelse

Mouse Monoclonal Antibody

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Cathelicidin
Applikationer Western Blot
Klassifikation Monoclonal
Klon C2
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene CAMP
Genadgangsnr. P49913
Gene Alias 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
Gensymboler CAMP
Værtsarter Mouse
Immunogen Gln31-Ser170 (Accession P49913), with N-terminal His Tag.
Oprensningsmetode Protein A/G
Mængde 100 μL
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 820
Målarter Human
Indhold og opbevaring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttype Antibody
Form Liquid
Isotype IgG2a κ
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