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Invitrogen™ Carbonic Anhydrase IX Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA580399

Produktkode 16337534

  • 2630.00 DKK / 100µL

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Beskrivelse

Beskrivelse

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Carbonic Anhydrase IX/CA9.

Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA IX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia. Therefore, CA IX has become a reliable histochemical marker of hypoxia.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

Carbonic Anhydrase IX
Polyclonal
Unconjugated
CA9
Ca9; CA-9; CAIX; CA-IX; Car9; Carbonate dehydratase IX; carbonic anhydrase 9; Carbonic anhydrase IX; carbonic dehydratase; G250; Membrane antigen MN; membrane antigen MN homolog; MN; MN/CA9; P54 / 58N; P54/58N; pMW1; RCC-associated antigen G250; RCC-associated protein G250; renal cell carcinoma-associated antigen G250
Rabbit
Antigen affinity chromatography, Protein A
RUO
768
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Western Blot
1 mg/mL
PBS with no preservative
Q16790
CA9
Recombinant Human Carbonic Anhydrase IX/CA9 Protein (Met1-Asp414).
100 μL
Primary
Human
Antibody
IgG
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