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Invitrogen™ Carbonic Anhydrase IX Polyclonal Antibody
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Artikelnummer. 16337534
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100 μL
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16337534 100 μL
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Artikelnummer. 16337534 Leverandør Invitrogen™ Leverandørnr. PA580399

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Beskrivelse

Rabbit Polyclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Carbonic Anhydrase IX/CA9.

Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA IX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia. Therefore, CA IX has become a reliable histochemical marker of hypoxia.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Carbonic Anhydrase IX
Applikationer ELISA, Western Blot
Klassifikation Polyclonal
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering PBS with no preservative
Gene CA9
Genadgangsnr. Q16790
Gene Alias Ca9; CA-9; CAIX; CA-IX; Car9; Carbonate dehydratase IX; carbonic anhydrase 9; Carbonic anhydrase IX; carbonic dehydratase; G250; Membrane antigen MN; membrane antigen MN homolog; MN; MN/CA9; P54 / 58N; P54/58N; pMW1; RCC-associated antigen G250; RCC-associated protein G250; renal cell carcinoma-associated antigen G250
Gensymboler CA9
Værtsarter Rabbit
Immunogen Recombinant Human Carbonic Anhydrase IX/CA9 Protein (Met1-Asp414).
Oprensningsmetode Antigen affinity chromatography, Protein A
Mængde 100 μL
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 768
Målarter Human
Indhold og opbevaring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttype Antibody
Form Liquid
Isotype IgG
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