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Invitrogen™ Carbonic Anhydrase IX Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA581331

Produktkode 16378354

  • 2630.00 DKK / 100µL

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Beskrivelse

Beskrivelse

This antibody has specificity for Mouse Carbonic Anhydrase IX/CA9.

Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA IX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia. Therefore, CA IX has become a reliable histochemical marker of hypoxia.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

Carbonic Anhydrase IX
Polyclonal
Unconjugated
Car9
Ca9; CA-9; CAIX; CA-IX; Car9; Carbonate dehydratase IX; carbonic anhydrase 9; Carbonic anhydrase IX; carbonic dehydratase; G250; Membrane antigen MN; membrane antigen MN homolog; MN; MN/CA9; P54 / 58N; P54/58N; pMW1; RCC-associated antigen G250; RCC-associated protein G250; renal cell carcinoma-associated antigen G250
Rabbit
Protein A, Antigen affinity chromatography
RUO
230099
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Immunohistochemistry (Paraffin)
0.22 mg/mL
PBS with 0.03% ProClin 300; pH 7
Q8VHB5
Car9
Recombinant Mouse Carbonic Anhydrase IX/CA9 Protein (Met1-Asp390).
100 μL
Primary
Mouse
Antibody
IgG
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