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Capsazepine, 98+%, Thermo Scientific™
A competitive antagonist for capsaicin and resiniferatoxin
Brand: Thermo Scientific Alfa Aesar J63055.MF
| Mængde | 50mg |
|---|
Beskrivelse
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
ApplicationsCapsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.
Solubility
Soluble in ethanol or DMSO
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
Kemiske identifikatorer
| 138977-28-3 | |
| 376.899 | |
| DRCMAZOSEIMCHM-UHFFFAOYSA-N | |
| 2733484 | |
| N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide |
| C19H21ClN2O2S | |
| MFCD00153778 | |
| capsazepine, capsazepin, n-2-4-chlorophenyl ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2h-2-benzazepine-2-carbothioamide, unii-lfw48my844, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide, 2-2-4-chlorophenyl ethylamino-thiocarbonyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-2-benzazepine, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2h-2-benzazepine-2-carbothioamide, capasazepine, tocris-0464 | |
| CHEBI:70773 | |
| C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O |
Tekniske data
| Capsazepine | |
| C19H21ClN2O2S | |
| 50mg | |
| Soluble in ethanol or DMSO | |
| C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O | |
| 376.899 | |
| CHEBI:70773 | |
| ≥99% |
| 138977-28-3 | |
| MFCD00153778 | |
| capsazepine, capsazepin, n-2-4-chlorophenyl ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2h-2-benzazepine-2-carbothioamide, unii-lfw48my844, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide, 2-2-4-chlorophenyl ethylamino-thiocarbonyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-2-benzazepine, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2h-2-benzazepine-2-carbothioamide, capasazepine, tocris-0464 | |
| DRCMAZOSEIMCHM-UHFFFAOYSA-N | |
| N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide | |
| 2733484 | |
| 376.9 |
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