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Capsazepine, 98+%

Artikelnummer. 15415329
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Artikelnummer. 15415329 Leverandør Thermo Scientific Alfa Aesar Leverandørnr. J63055.MF
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Forventet forsendelse: 08-10-2026
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Beskrivelse

A competitive antagonist for capsaicin and resiniferatoxin | CAS: 138977-28-3 | C19H21ClN2O2S | 376.899 g/mol

Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.

Solubility
Soluble in ethanol or DMSO

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 138977-28-3
Molekylær formel C19H21ClN2O2S
Molekylvægt (g/mol) 376.899
MDL nummer MFCD00153778
InChI nøgle DRCMAZOSEIMCHM-UHFFFAOYSA-N
Synonym capsazepine, capsazepin, n-2-4-chlorophenyl ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2h-2-benzazepine-2-carbothioamide, unii-lfw48my844, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide, 2-2-4-chlorophenyl ethylamino-thiocarbonyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-2-benzazepine, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2h-2-benzazepine-2-carbothioamide, capasazepine, tocris-0464
PubChem CID 2733484
ChEBI CHEBI:70773
IUPAC navn N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide
SMIL C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O

Tekniske data

Kemisk navn eller materiale Capsazepine
Smeltepunkt 159°C to 161°C
Farve White
Mængde 50 mg
Opløselighedsinformation Soluble in ethanol or DMSO
Formel vægt 376.9
Procent renhed ≥99%
Fysisk form Powder

RUO – Research Use Only

Produkttitel
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