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DiscoverX cAMP Hunter™ eXpress GPR109A CHO-K1 GPCR Assay

Artikelnummer. 17324639
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Mængde:
200 dp (2 x 96-brønds)
Pakningsstørrelse:
1 sæt
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Artikelnummer. Mængde unitSize
17324639 200 dp (2 x 96-brønds) 1 sæt
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Artikelnummer. 17324639 Leverandør DiscoverX Leverandørnr. 950122E2CP2M

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Beskrivelse

The cAMP Hunter™ eXpress GPR109A CHO-K1 GPCR Assay measures GPR109A (GPCR) activity via decreased levels of intracellular cAMP. eXpress kits contain all assay materials: cells, reagents, and plates.

The cAMP Hunter™ GPR109A eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. nicotinic acid) based activation of GPR109A GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype GPR109A , a naturally Gi/Go coupled GPCR. Upon activation of GPR109A , the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Tekniske data

Assay Entry CHO-K1
Til brug med (applikation) Assay-Ready eXpress Kits
Primær agonist Nicotinic Acid
Mængde 200 dp (2 x 96-brønds)
Målindgang GPR109A
Cellelinje CHO-K1
Mål GPR109A
Produkttitel
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