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Camostat methanesulfate, 98%, Thermo Scientific™

An orally active synthetic serine protease inhibitor

Brand:  Thermo Scientific Alfa Aesar J62362.ME

Mængde 500mg

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Produktkode 15444759

  • 4164.24 DKK / 500mg

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Beskrivelse

Beskrivelse

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
It is used as a protease and Trypsin inhibitor. Furthermore it was found that this water induction and bicarbonate secretion increase was achieved via direct regulation of ductular cells of the dog pancreas. Other studies have shown Camostat mesylate to suppress spinal Fos expression in the rat, which is a marker for neuronal activation. In addition it was shown that this compound may prevent or depress pancreatitis-induced referred allodynia/hyperalgesia in rat models. Camostat mesylate has also demonstrated the ability to prevent Trypsin attack of microspheres, which causes the degradation product N-benzoyl-dl-arginine. Camostat mesylate is an inhibitor of KLK, plasminogen, Prothrombin and Trypsin.

Solubility
Soluble in water (100 mM), DMSO (100 mM), and ethanol (<1mg/mL).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY
Tekniske data

Kemiske identifikatorer

59721-29-8
494.52
FSEKIHNIDBATFG-UHFFFAOYSA-N
5284360
CS(O)(=O)=O.CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(C=C2)N=C(N)N)C=C1
C21H26N4O8S
MFCD00941410
camostat mesylate, camostat mesilate, camostat methanesulfonate, camostat monomethanesulfonate, foipan, unii-451m50a1eq, dsstox_cid_238, dsstox_rid_75452, dsstox_gsid_20238
4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-[(diaminomethylidene)amino]benzoate; methanesulfonic acid

Tekniske data

Camostat methanesulfate
C21H26N4O8S
500mg
camostat mesylate, camostat mesilate, camostat methanesulfonate, camostat monomethanesulfonate, foipan, unii-451m50a1eq, dsstox_cid_238, dsstox_rid_75452, dsstox_gsid_20238
FSEKIHNIDBATFG-UHFFFAOYSA-N
4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-[(diaminomethylidene)amino]benzoate; methanesulfonic acid
5284360
98%
59721-29-8
MFCD00941410
14,1728
Soluble in water (100 mM),DMSO (100 mM),and ethanol (<1mg/ml).
CS(O)(=O)=O.CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(C=C2)N=C(N)N)C=C1
494.52
494.52
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