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Camostat methanesulfate, 98%

Artikelnummer. 15444759
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Artikelnummer. 15444759 Leverandør Thermo Scientific Alfa Aesar Leverandørnr. J62362.ME
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Forventet forsendelse: 05-10-2026
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Beskrivelse

An orally active synthetic serine protease inhibitor | CAS: 59721-29-8 | C21H26N4O8S | 494.52 g/mol

It is used as a protease and Trypsin inhibitor. Furthermore it was found that this water induction and bicarbonate secretion increase was achieved via direct regulation of ductular cells of the dog pancreas. Other studies have shown Camostat mesylate to suppress spinal Fos expression in the rat, which is a marker for neuronal activation. In addition it was shown that this compound may prevent or depress pancreatitis-induced referred allodynia/hyperalgesia in rat models. Camostat mesylate has also demonstrated the ability to prevent Trypsin attack of microspheres, which causes the degradation product N-benzoyl-dl-arginine. Camostat mesylate is an inhibitor of KLK, plasminogen, Prothrombin and Trypsin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as a protease and Trypsin inhibitor. Furthermore it was found that this water induction and bicarbonate secretion increase was achieved via direct regulation of ductular cells of the dog pancreas. Other studies have shown Camostat mesylate to suppress spinal Fos expression in the rat, which is a marker for neuronal activation. In addition it was shown that this compound may prevent or depress pancreatitis-induced referred allodynia/hyperalgesia in rat models. Camostat mesylate has also demonstrated the ability to prevent Trypsin attack of microspheres, which causes the degradation product N-benzoyl-dl-arginine. Camostat mesylate is an inhibitor of KLK, plasminogen, Prothrombin and Trypsin.

Solubility
Soluble in water (100 mM), DMSO (100 mM), and ethanol (<1mg/mL).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 59721-29-8
Molekylær formel C21H26N4O8S
Molekylvægt (g/mol) 494.52
MDL nummer MFCD00941410
InChI nøgle FSEKIHNIDBATFG-UHFFFAOYSA-N
Synonym camostat mesylate, camostat mesilate, camostat methanesulfonate, camostat monomethanesulfonate, foipan, unii-451m50a1eq, dsstox_cid_238, dsstox_rid_75452, dsstox_gsid_20238
PubChem CID 5284360
IUPAC navn 4-{2-[(dimethylcarbamoyl)methoxy]-2-oxoethyl}phenyl 4-[(diaminomethylidene)amino]benzoate; methanesulfonic acid
SMIL CS(O)(=O)=O.CN(C)C(=O)COC(=O)CC1=CC=C(OC(=O)C2=CC=C(C=C2)N=C(N)N)C=C1

Tekniske data

Kemisk navn eller materiale Camostat methanesulfate
Smeltepunkt 164°C to 168°C
Farve White
Mængde 500 mg
Merck Index 14,1728
Opløselighedsinformation Soluble in water (100 mM),DMSO (100 mM),and ethanol (<1mg/ml).
Formel vægt 494.52
Procent renhed 98%
Fysisk form Powder

RUO – Research Use Only

Produkttitel
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