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Tocris Bioscience™ Calcipotriol
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Artikelnummer. 18094602
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10 mg
50 mg
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18094602 10 mg
18064182 50 mg
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Artikelnummer. 18094602 Leverandør Tocris Bioscience™ Leverandørnr. 2700/10

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Description

Vitamin D3 analog

Calcipotriol is a vitamin D3 analog that displays minimal effects on calcium homeostasis. Regulates cell differentiation and proliferation; exhibits antiproliferative activity against human HL-60, HL60/MX2, keratinocytes, MCF-7, T47D, SCC-25, and mouse WEHI-3 cancer cell lines. Calcipotriol suppresses skin cancer development in mice in a thymic stromal lymphopoietin (TSLP)-dependent manner. Calcipotriol promotes the differentiation of keratinocytes. In human T cells and in psoriatic skin, Calcipotriol increases IL-10 secretion, induces secretion of type 2 cytokines by T cells and modulates the differentiation of dendritic cells and T cells.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 112965-21-6
Molekylær formel C27H40O3

Specifications

Kemisk navn eller materiale Calcipotriol
Mængde 10 mg
Formel vægt 412.6
Renhed >98%
Molekylvægt (g/mol) 412.61
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