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C/EBP alpha Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand: Invitrogen PA587519

2616.79 DKK valid until 2025-03-29
Use promo code "24111" to get your promotional price.

Product Code. 16565991

4010.00 DKK / 100µL

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Description

Immunogen sequence: APAGPGGAVM PGGAHGPPPG YGCAAAGYLD GRLEPLYERV GAPALRPLVI KQEPREEDEA KQLALAGLFP Positive Samples: mouse lung; Cellular Location: Nucleus, Nucleus, nucleolus

The C/EBP (CCAAT/enhancer binding protein) family of transcription factors--alpha, beta, delta, and epsilon)--are widely expressed proteins found in a variety of tissues. These domains contain an evolutionarily conserved five-amino acid motif (the regulatory domain motif RDM) that conforms to the consensus sequence (I/V/L) KXEP. One of the major roles of these transcription factors is that of metabolic regulation in liver and fat cells. Studies suggest that these transcription factors act in a cascade aiding in the development of the adipose cell. Three C/EBP beta isoforms (LAP*, LAP, and LIP) arise from different translation initiation and display different function in gene regulation. From a neurological standpoint, C/EBPs have been implicated in the mediation of nerve growth factor, altering synaptic plasticity, and mediation of inflammatory response in AD patients.

Specifications

Antigen	C/EBP alpha
Classification	Polyclonal
Conjugate	Unconjugated
Gene	CEBPA
Gene Alias	C EBP, C/EBP, c/EBP alpha, C/EBPa, C/ebpalpha, C/EBP-alpha, CAAT/enhancer-binding protein DNA-binding protein, CAAT/enhancer-binding protein, DNA-binding protein, CBF-A, CCAAT enhancer binding protein alpha, CCAAT/enhancer binding protein (C/EBP), alpha, CCAAT/enhancer binding protein alpha, CCAAT/enhancer binding protein, alpha, CCAAT/enhancer-binding protein alpha, Cebp, Cebpa, DBPCEP, OTTHUMP00000220269
Host Species	Rabbit
Purification Method	Affinity Chromatography
Regulatory Status	RUO
Gene ID (Entrez)	1050, 12606, 24252
Content And Storage	-20° C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	Immunohistochemistry (Paraffin), Western Blot
Concentration	0.76 mg/mL
Formulation	PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.	P05554, P49715, P53566
Gene Symbols	CEBPA
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 111-180 of human CEBPA (NP_0043552)
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human, Mouse, Rat
Product Type	Antibody
Isotype	IgG

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C/EBP alpha Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated

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C/EBP alpha Polyclonal Antibody, Invitrogen™

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