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STEMCELL Technologies Butein

Artikelnummer. 17100232
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Mængde:
10 mg
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17100232 10 mg
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Artikelnummer. 17100232 Leverandør STEMCELL Technologies Leverandørnr. 73464

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Beskrivelse

NF-κB pathway inhibitor; Stabilizes IκB

  • Butein is a plant polyphenol, tetrahydroxychalcone that inhibits nuclear factor (NF)-κB (Yang et al; Pandey et al. 2007)
  • Butein has been shown to prevent phosphorylation and degradation of TNF-dependent IκBα, an inhibitory subunit of NF-κB (IC50 = 38 μM; Orlikova et al.) Butein also inhibits 5-lipoxygenase (IC50 = 0.01 μM; Sogawa et al.), the enoyl-acyl-carrier protein reductase of Plasmodium falciparum (Ki = 2.97 μM; Sharma et al.), angiotensin-converting enzyme (IC50 = 0.73 mM; Bonesi et al.), and SRC kinase (Pandey et al. 2009)

Tekniske data

CAS 487-52-5
Synonym 2',3,4,4'-Tetrahydroxychalcone
Mængde 10 mg
Molekylær formel C15H12O5
Renhed ≥95%
Produkttitel
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