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BRD4770, MedChemExpress

Artikelnummer. 16457146
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16457146 100 mg
16447148 10 mg
16413177 50 mg
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Artikelnummer. 16457146 Leverandør Medchem Express Leverandørnr. HY16705

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Beskrivelse

MedChemExpress BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 μM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence.

BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 μM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence.

Tekniske data

Kemisk navn eller materiale BRD4770
CAS 1374601-40-7
Farve White
Renhedsgrad noter Research
Molekylær formel C25H23N3O3
Mængde 100 mg
Opløselighedsinformation DMSO : 33.33 mg/mL (80.61 mM; Need ultrasonic)
SMIL O=C(C1=CC=C2C(N=C(NC(C3=CC=CC=C3)=O)N2CCCC4=CC=CC=C4)=C1)OC
Molekylvægt (g/mol) 413.47
Formel vægt 413.47
Procent renhed 98.59%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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