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BMX-IN-1, MedChemExpress

Artikelnummer. 16494127
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2 mg
5 mg
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50 mg
Pakningsstørrelse:
10mg
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Artikelnummer. 16494127 Leverandør Medchem Express Leverandørnr. HY80002

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Beskrivelse

MedChemExpress BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.

BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.

Tekniske data

Kemisk navn eller materiale BMX-IN-1
CAS 1431525-23-3
Farve Off-White
Renhedsgrad noter Research
Molekylær formel C29H24N4O4S
Mængde 50 mg
Synonym BMX kinase inhibitor
Opløselighedsinformation DMF : 10 mg/mL (19.06 mM; Need ultrasonic) ∣DMSO : 8.33 mg/mL (15.88 mM; Need ultrasonic)
SMIL O=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CC=C(NS(=O)(C)=O)C=C4)C=C32)C5=CC=C(C)C(NC(C=C)=O)=C5
Molekylvægt (g/mol) 524.59
Formel vægt 524.59
Procent renhed 96.27%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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