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BMS-986020, MedChemExpress

Artikelnummer. 16499656
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Artikelnummer. 16499656 Leverandør Medchem Express Leverandørnr. HY100619

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MedChemExpress BMS-986020 (AM152) is a high-affinity and selective lysophosphatidic acid receptor 1 (LPA1) antagonist. BMS-986020 inhibits bile acid and phospholipid transporters with IC50s of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF).

BMS-986020 (AM152) is a high-affinity and selective lysophosphatidic acid receptor 1 (LPA1) antagonist. BMS-986020 inhibits bile acid and phospholipid transporters with IC50s of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF).

Tekniske data

Kemisk navn eller materiale BMS-986020
Fysisk form Solid
CAS 1257213-50-5
Farve White
Mængde 50 mg
Renhedsgrad noter Research
Molekylær formel C29H26N2O5
Til brug med (applikation) COVID-19-immunoregulation
Synonym AM152
Opløselighedsinformation DMSO : 250 mg/mL (518.10 mM; Need ultrasonic)
SMIL O=C(C1(C2=CC=C(C3=CC=C(C4=C(NC(O[C@@H](C5=CC=CC=C5)C)=O)C(C)=NO4)C=C3)C=C2)CC1)O
Molekylvægt (g/mol) 482.53
Formel vægt 482.53
Procent renhed 98.0%
Grad Research
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Research purposes only

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