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Tocris Bioscience™ BMS 299897

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Mængde:
10 mg
Description
Orally active, potent γ-secretase inhibitor (IC50 = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC50 values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo. Exhibits no Notch toxicity. Brain penetrant.
Specifications
Specifications
| Kemisk navn eller materiale | BMS 299897 |
| CAS | 290315-45-6 |
| Mængde | 10 mg |
| Molekylær formel | C24H21ClF3NO4S |
| Formel vægt | 511.94 |
| Renhed | >98% |
| Molekylvægt (g/mol) | 511.94 |
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