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ACROBiosystems Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, His, Avitag™ (SPR verified)

Artikelnummer. 17156311
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Mængde:
200 μg
25 μg
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Artikelnummer. Mængde
17156311 25 μg
17146311 200 μg
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Artikelnummer. 17156311 Leverandør ACROBiosystems Leverandørnr. FCMH82W725ug

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Biotinylated Protein

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

Biotinylated Human FCGRT&B2M Heterodimer Protein, His,Avitag, produced by co-expression of FCGRT and B2M, has a calculated MW of 34.2 kDa (FCGRT) and 11.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus, followed by an Avi tag

Tekniske data

Adgangsnummer NP_001129491.1 (FCGRT) and NP_004039.1 (B2M)
Molekylvægt (g/mol) 34.2 kDa (FCGRT) and 11.7 kDa (B2M)
Mængde 25 μg
Kilde Biotinylated Human FCGRT&B2M; Heterodimer Protein, His,Avitag (FCM-H82W7) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M) (Accession # P55899-1 (FCGRT) and P61769-1 (B2M)).
Immunogen Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M)
Opbevaringskrav -20°C
Gene Alias FcRn,FCGRT and B2M
Fælles navn FcRn (FCGRT and B2M)
Konjugeret Precision Avi
Arter Human
Protein tag His Tag and Avi Tag
Buffer PBS, pH7.4
Endotoksin niveau Less than 1.0 EU / μg by the LAL method.
Udtrykssystem HEK293
Form Powder
Protein undertype MABSol™ Biotin Labeled Proteins
Renhed eller kvalitetsklasse >95% as determined by SDS-PAGE
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