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  7. Bilirubin 97%, Thermo Scientific Chemicals

Bilirubin 97%, Thermo Scientific Chemicals

Artikelnummer. 11498137
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Artikelnummer. 11498137 Leverandør Thermo Scientific Alfa Aesar Leverandørnr. A17522.03
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Beskrivelse

Bilirubin 97%, CAS # 635-65-4, is a tetrapyrroliccompound found in bile that is a product of heme catabolism.

Bilirubin is widely utilized to monitor the liver function and their disease, such as hepatitis or cirrhosis; or the effects of medicines which are damage the liver. It acts as a pigment in certain algae to capture light energy. Its double bonds are isomerizes in the presence of light, which is employed in phototherapy of jaundiced newborns babies. It is used to detect the blocking in bile ducts.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Bilirubin is a degradation product of heme following the activity of heme oxidase. Bilirubin is produced in the reticuloendothelial system and conjugated in the liver. It appears as an orange-yellow pigment that is secreted in the bile
  • High levels of unconjugated bilirubin can result in jaundice, a condition of the yellowing of skin and eyes. This can be toxic and may be a sign of severe liver disease
  • Bilirubin has been seen to have functions including cell signaling, metabolism modulation, and immune regulation
  • It has protective antioxidant activity at moderate levels

Application

  • Bilirubin is widely used in studies of liver function and disease, such as hepatitis or cirrhosis
  • As an antioxidant, bilirubin has been studied in protection against H2O2-mediated cell death
  • It can be used as a scavenger of reactive oxygen species (ROS) or as an inhibitor of NADPH oxidase
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 635-65-4
Molekylær formel C33H36N4O6
Molekylvægt (g/mol) 584.67
MDL nummer MFCD00005499
InChI nøgle BPYKTIZUTYGOLE-IFADSCNNSA-N
Synonym bilirubin, hematoidin, hemetoidin, bilirubin ix-alpha, principal bile pigment, unii-rfm9x3lj49, bilirubin ixalpha, 21h-biline-8,12-dipropanoic acid, 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo, rfm9x3lj49, biline-8,12-dipropionic acid, 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl
PubChem CID 5280352
ChEBI CHEBI:16990
IUPAC navn 3-[2-[[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
SMIL CC1=C(C=C)\C(NC1=O)=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\C=C2/NC(=O)C(C=C)=C2C)N1

Tekniske data

Kemisk navn eller materiale Bilirubin
Mængde 1 g
Beilstein 74376
Følsomhed Light sensitive
Merck Index 14,1218
Opløselighedsinformation Soluble in chloroform,benzene,chlorobenzene,carbon disulfide,alkaline solutions and aqueous acid. Slightly soluble in ethanol and ether. Insoluble in water.
Formel vægt 584.68
Procent renhed 97%

RUO – Research Use Only

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