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Bexarotene, 98%, Thermo Scientific Chemicals

Artikelnummer. 15485879
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Mængde:
100 mg
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15485879 100 mg
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Artikelnummer. 15485879 Leverandør Thermo Scientific Alfa Aesar Leverandørnr. J63701.MC
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Beskrivelse

Synthetic retinoid analog with specific affinity for the retinoid X receptor

Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer's model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

Solubility
Soluble in DMSO and ethanol

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 153559-49-0
Molekylær formel C24H28O2
Molekylvægt (g/mol) 348.49
MDL nummer MFCD00932428
InChI nøgle NAVMQTYZDKMPEU-UHFFFAOYSA-N
Synonym bexarotene, targretin, targrexin, targretyn, targret, bexarotenum, bexarotene usan, bexaroteno, bexaroten, targretin-gel
PubChem CID 82146
ChEBI CHEBI:50859
IUPAC navn 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
SMIL CC1=CC2=C(C=C1C(=C)C1=CC=C(C=C1)C(O)=O)C(C)(C)CCC2(C)C

Tekniske data

Kemisk navn eller materiale Bexarotene
Smeltepunkt 220°C to 225°C
Farve White
Mængde 100 mg
Merck Index 14,1194
Opløselighedsinformation Soluble in DMSO and ethanol
Formel vægt 348.48
Procent renhed ≥99%
Fysisk form Powder

RUO – Research Use Only

Produkttitel
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