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  6. Invitrogen™ beta-3 Tubulin Monoclonal Antibody (2G10)

Invitrogen™ beta-3 Tubulin Monoclonal Antibody (2G10)
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Artikelnummer. 15234347
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Mængde:
100 μg
20 μL
Pakningsstørrelse:
20µL
Hver
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15234347 100 μg Hver
15356241 20 μL 20µL
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Artikelnummer. 15234347 Leverandør Invitrogen™ Leverandørnr. MA1118
Styrk proteomik
Brug rabatkode 28003
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Beskrivelse

Mouse Monoclonal Antibody

MA1-118 was successfully used to detect E18 Sparague Dawley primary cortical neurons. MA1-118 can be used for immunofluorescence analysis of beta III tubulin in the ectoderm derived from human embryonic stem cells. Western blot analysis of MA1-118 detects an ~50 kDa protein in neuronal-type cells. In bovine, a unknown band at ~32 kDa is also detected. MA1-118 shows specificity to beta-3 Tubulin and is non-reactive to lysates from non-neuronal cell types (e.g. HeLa cell lysate).

The betaIII-tubulin isoform is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
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Tekniske data

Antigen beta-3 Tubulin
Applikationer Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Multiplex Immunohistochemistry
Klassifikation Monoclonal
Klon 2G10
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene TUBB3
Genadgangsnr. Q13509, Q2T9S0, Q4QRB4, Q9ERD7
Gene Alias 3200002H15Rik; beta 3 tubulin; beta tubulin 3; beta-4; betaIII-tubulin; CDCBM; CDCBM1; CFEOM3; CFEOM3A; class III beta-tubulin; FEOM3; I79_000194; LOC100341581; M(beta)3; M(beta)6; mc1R; melanocortin receptor 1; Neuron specific beta III Tubulin; neuron-specific class III beta-tubulin; TUBB; Tubb3; TUBB4; tubulin beta; tubulin beta 3 class III; Tubulin beta-3; tubulin beta-3 chain; Tubulin beta-4; Tubulin beta-4 chain; tubulin beta-III; tubulin, beta 3 class III; tubulin, beta, 3; tubulin, beta, 4; Unknown (protein for MGC:134115)
Gensymboler LOC100341581, TUBB3
Værtsarter Mouse
Immunogen A synthetic peptide corresponding to amino acids 436-450 from rat neuronal specific beta-3 tubulin.
Oprensningsmetode Protein A
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 100341581, 100732882, 100760055, 10381, 106509340, 22152, 246118, 768070
Målarter Human, Mouse, Rat, Rabbit, Bovine, Hamster, Pig, Guinea Pig
Indhold og opbevaring -20°C
Produkttype Antibody
Form Liquid
Isotype IgG2a
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