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Tocris Bioscience™ BC-LI-0186
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Artikelnummer. 18796876
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25 mg
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Artikelnummer. Mængde
18796876 25 mg
18776456 5 mg
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Artikelnummer. 18796876 Leverandør Tocris Bioscience™ Leverandørnr. 6791/25

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Beskrivelse

Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor

BC-LI-0186 is a potent and high affinity leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor (IC50 = 46.1 nM; Kd = 42.1 nM for binding to LRS). Inhibits mTOR complex 1 activity by blocking binding to LRS without affecting catalytic activity. Inhibits leucine-induced translocation of LRS to the lysosome.
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale 4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1 H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide
CAS 695207-56-8
Mængde 25 mg
Mål Ras GTPase Inhibitors
Molekylær formel C22H27N3O4S
Formel vægt 3939
Renhed 98%
Produkttitel
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