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(±)-Bay K 8644, Tocris Bioscience™

CaV1.x activator
Brand: Tocris Bioscience 1544/10
Beskrivelse
L-type Ca2+ channel activator (EC50 = 17.3 nM). Has positive inotropic, vasoconstrictive and behavioral effects in vivo. In combination with BIX-01294 (Cat. No. 3364), helps generate induced pluripotent stem cells (iPSCs) from mouse embryonic fibroblasts (MEFs). Inhibits autophagy.(S)-(-)-Enantiomer and (R)-(+)-Enantiomer also available.
Tekniske data
| (±)-Bay K 8644 | |
| C16H15F3N2O4 | |
| methyl 2,6-dimethyl-5-nitro-4-2-trifluoromethyl phenyl-1,4-dihydropyridine-3-carboxylate, 3-pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-2-trifluoromethyl phenyl-, methyl ester, 1,4-dihydro-2,6-dimethyl-5-nitro-4-2′-trifluoromethyl phenyl-3-pyridinecarboxylic acid methyl ester, bay-k-8644, +--isomer, opera_id_789, d01rad, y-bay k 8644, r-+-1,4-dihydro-2,6-dimethyl-5-nitro-4-2-trifluoromethyl phenyl-3-pyridinecarboxylic acid methyl ester | |
| CC1=C(C(C(=C(N1)C)[N+](=O)[O-])C2=CC=CC=C2C(F)(F)F)C(=O)OC | |
| 356.301 | |
| CHEBI:34555 | |
| >99% |
| 71145-03-4 | |
| 10mg | |
| ZFLWDHHVRRZMEI-UHFFFAOYSA-N | |
| methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate | |
| 2303 | |
| 356.3 |
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