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Invitrogen™ BAX Recombinant Rabbit Monoclonal Antibody (5K8X4)
GREENER_CHOICE

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA535342

Produktkode 17126003

  • 3630.00 DKK / 100µL

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Immunogen sequence: MDGSGEQPRG GGPTSSEQIM KTGALLLQGF IQDRAGRMGG EAPELALDPV PQDASTKKLS ECLKRIGDEL DSNMELQRMI AAVDTDSPRE VFFRVAADMF.

BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa). BAX is a member of the BCL-2 family of proteins, which function as regulators of apoptosis. Overexpression of BAX functions to promote cell death. BAX can form homodimers and is also able to heterodimerize with other BCL-2 related proteins.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

BAX
Recombinant Monoclonal
0.6 mg/mL
PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
Q07812, Q07813, Q63690
BAX
Synthetic peptide.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
ELISA, Immunohistochemistry (Paraffin), Western Blot
5K8X4
Unconjugated
BAX
apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52
Rabbit
Affinity Chromatography
RUO
12028, 24887, 581
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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