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Invitrogen™ BAK Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5106855
Denne vare kan ikke returneres.
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Beskrivelse
Antibody detects endogenous levels of total Bak.
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Tekniske data
| BAK | |
| Polyclonal | |
| Unconjugated | |
| BAK1 | |
| Apoptosis regulator BAK; BAK; Bak1; BAK-LIKE; BCL2 antagonist/killer 1; Bcl2 homologous antagonist/killer; Bcl-2 homologous antagonist/killer; BCL2-antagonist/killer 1; BCL2L7; bcl2-L-7; BCL2-like 7 protein; BCL2-like 7protein; bcl-2-like protein 7; Bcl-2-likeous antagonist/killer; CDN1; MGC117255; MGC3887; N-Bak; N-BAK1; pro-apoptotic protein BAK | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 116502, 12018, 578 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O08734, Q16611 | |
| BAK1 | |
| A synthesized peptide derived from human BAK1(Accession Q16611), corresponding to amino acid residues M1-E33. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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Produkttitel
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