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STEMCELL Technologies Bafilomycin A1

Inhibits autophagy and vacuolar H+-ATPase (V-ATPase)

Brand:  STEMCELL Technologies 74242

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Product Code. 17140352

  • 4436.10 DKK / 500µg

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Description

Description

  • Bafilomycin A1 is a macrolide antibiotic drug and autophagy inhibitor
  • It prevents the acidification of autophagosomes via the inhibition of vacuolar H+-ATPase (V-ATPase; Klionsky et al.)
  • Inhibits the proteolytic degradation associated with autophagy in human mesenchymal stem cells (Oliver et al.)
  • At low concentrations, it inhibits autophagy and promotes apoptotic cell death in pediatric B cell acute lymphoblastic leukemia (B-ALL) cells (Yuan et al.)
Specifications

Specifications

88899-55-2
500 μg
≥95%
NSC 381866
C35H58O9
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