missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ BacMam Histone H3 Reagent

The BacMam Histone H3 Reagent provides a convenient genetic delivery tool for the expression of GFP-Histone H3 fusion protein in your cell background of interest.

Brand:  Invitrogen™ A14154

Product Code. 12073569

  • 22310.00 DKK / 100mL
Estimated Shipment: 30-10-2024
to see stock.
Explore more special offers
Add to basket
This item is not returnable. View return policy

Description

Description

The BacMam Histone H3 Reagent provides a convenient genetic delivery tool for the expression of GFP-Histone H3 fusion protein in your cell background of interest. The GFP fusion enables sensitive detection of post-translational modifications using LanthaScreen™ TR-FRET Cellular Assay technology.

The BacMam Histone H3 Reagent Lets You:

  • Use your cell background of choice with the portability of BacMam
  • Conserve precious cell samples with the miniaturizable homogenous assay format
  • Identify more relevant inhibitors since the methyl transferases and demethylases are in their natural protein complexes
  • Improve data quality with the advantages of TR-FRET

Get More Physiologically Relevant Results

The BacMam Histone H3 allows the investigation of post-translational modifications of histone H3 in your choice of cellular backgrounds, including primary cells. This enables screening for potential inhibitors of histone-modifying enzymes such as kinases, acetylases, deacetylases, methyl transferases, and demethylases in their natural complexes in a physiologically relevant cell type.

BacMam and LanthaScreen™ Convenience Saves Sample and Time

When used with a LanthaScreen™ Tb-anti-Histone H3 antibody against a specific modification, assays can be run in a fully homogenous, addition-only format without any of the washing, lysate transfer, or separation procedures required for traditional methods such as Western blotting and ELISA. By using the same BacMam reagent for GFP-Histone H3, a variety of histone H3 modifications (Ph, Me, Ac) can be monitored just by exchanging the Terbium (Tb) labeled antibody. In addition, the application of the LanthaScreen™ technology includes all of the advantages of TR-FRET detection, including reduced data noise, less interference from fluorescent compounds, and high sensitivity, allowing the use of fewer cells.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Store the BacMam Histone H3 Reagent at 4°C
100 mL
Wet Ice
Baculovirus (BacMam System)
Liquid
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers

For Research Use Only. Not for use in diagnostic procedures.