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Azithromycin dihydrate, Thermo Scientific™
Azithromycin dihydrate, CAS # 117772-70-0, is an azalide derived from erythromycin that shows antibacterial activity.
Brand: Thermo Scientific Alfa Aesar J66740.06
2006.00 DKK valid until 2026-07-03
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| Mængde | 5g |
|---|
Denne vare kan ikke returneres.
Se returpolitik
Beskrivelse
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• Azithromycin dihydrate is the dihydrate form of azithromycin, an azalide derived from erythromycin, that shows antibacterial activity
• Azithromycin dihydrate reversibly binds to the 23S rRNA of the 50S ribosomal subunit of the bacterial ribosome of susceptible microorganisms, inhibiting the translocation step of protein synthesis by preventing the assembly of the 50S ribosomal subunit. This inhibits bacterial protein synthesis and cell growth, causing cell death
Application
• Azithromycin dihydrate shows anti-immunomodulatory and anti-inflammatory activities
• It shows antimalarial activity against Plasmodium falciparum and P. vivax, which are multidrug-resistant species
• In the laboratory, azithromycin dihydrate has been used in blocking buffer for indirect immunofluorescence
• It has been used in U87 cells for cell viability assay and flow cytometry analysis to study the Zika virus infection in glial cells
• Azithromycin dihydrate has been used in experiments to compare its antibacterial activity with PYRRO-C3D against Streptococcus pneumoniae biofilms
Tekniske data
| Azithromycin dihydrate | |
| White | |
| >110°C (230°F) | |
| C38H76N2O14 | |
| 717°C | |
| Soluble in DMSO at 20mg/mL; Also soluble in chloroform or ethylene chloride | |
| CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O.O.O | |
| 785.026 | |
| 785.01 |
| 117772-70-0 | |
| 5g | |
| Air sensitive | |
| MFCD01862248 | |
| N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A; CP-62993 | |
| SRMPHJKQVUDLQE-GTCGPNQGSA-N | |
| (2R,3S,4S,5R,8R,10R,11R,12S,13R,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-o | |
| 131845180 | |
| 98% |
Sikkerhed og håndtering
Produktidentifikator
Signalord
Farekategori
Faresætning
Sikkerhedssætning
Supplerende oplysninger
- Azithromycin dihydrate
Signalord
- Fare
Farekategori
- Respiratorisk sensibiliserende stof Kategori 1
- Hudsensibilisering Kategori 1
Faresætning
- H317-Kan forårsage allergisk hudreaktion.
- H334-Kan forårsage allergi- eller astmasymptomer eller åndedrætsbesvær ved indånding.
Sikkerhedssætning
- P280-Bær beskyttelseshandsker/beskyttelsestøj/øjenbeskyttelse/ ansigtsbeskyttelse.
- P284-[I tilfælde af utilstrækkelig ventilation], anvend åndedrætsværn.
- P302+P352-VED KONTAKT MED HUDEN: Vask med rigeligt vand/.
- P304+P340-VED INDÅNDING: Flyt personen til et sted med frisk luft og sørg for, at vejrtrækningen lettes.
- P333+P313-Ved hudirritation eller udslet: Søg lægehjælp.
- P342+P311-Ved luftvejssymptomer: Ring til en GIFTINFORMATION/læge/ .
- P362+P364-Alt tilsmudset tøj tages af og vaskes inden genanvendelse.
Supplerende oplysninger
- MIXTURE LIST-Contain: Azithromycin hydrate
Produkttitel
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