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Atrophin 1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA5101451
This item is not returnable.
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Description
Antibody detects endogenous levels of total Atrophin 1.
Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
Specifications
| Atrophin 1 | |
| Polyclonal | |
| Unconjugated | |
| ATN1 | |
| ATN1; Atr1; atrophin 1; Atrophin1; atrophin-1; B37; D12S755E; dentatorubral pallidoluysian atrophy; dentatorubral-pallidoluysian atrophy protein; Dentatorubral-pallidoluysian atrophy protein homolog; Drpla; HRS; NOD | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 13498, 1822, 29515 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O35126, P54258, P54259 | |
| ATN1 | |
| A synthesized peptide derived from human ATN1(Accession P54259), corresponding to amino acid residues T92-E142. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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Product Title
Atrophin 1 Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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