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AS601245, MedChemExpress

Artikelnummer. 16497067
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16497067 5 mg
16434358 10 mg
16400687 50 mg
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Artikelnummer. 16497067 Leverandør Medchem Express Leverandørnr. HY11010

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Beskrivelse

MedChemExpress AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties.

AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties.

Tekniske data

Kemisk navn eller materiale AS601245
Fysisk form Solid
CAS 345987-15-7
Farve Yellow
Mængde 5 mg
Renhedsgrad noter Research
Molekylær formel C20H16N6S
Til brug med (applikation) Cancer-Kinase/protease
Opløselighedsinformation DMSO : 10 mg/mL (26.85 mM; Need ultrasonic)
SMIL N#CC(C1=CC=NC(NCCC2=CC=CN=C2)=N1)C3=NC4=CC=CC=C4S3
Molekylvægt (g/mol) 372.45
Formel vægt 372.45
Procent renhed 98.7%
Grad Research
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Research purposes only

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