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Tocris Bioscience™ ArMan
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2 mg
Beskrivelse
ArMan is an aryl mannoside targeting ligand that can be functionalised to the surface of virus like particles (VLPs) via click chemistry. Functionalised particles can be used to target DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin) dendritic cells to promote selective coengagement of DC-SIGN and TLR7, resulting in a Th1-type immune response. In vivo, immunization with VLP-ArMan-OvaI/II significantly inhibits tumor growth in a murine melanoma model.
Tekniske data
Tekniske data
| Kemisk navn eller materiale | N-(4-(((2R,3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenethyl)pent-4-ynamide |
| Mængde | 2 mg |
| Mål | Buffers, Chelators and Reagents |
| Molekylær formel | C19H25NO7 |
| Renhed | 98% |
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