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Invitrogen™ APRIL Monoclonal Antibody (2C2C11)

Artikelnummer. 17470793 Shop alle Thermo Scientific produkter
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17470793 100 μg
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Artikelnummer. 17470793 Leverandør Invitrogen™ Leverandørnr. MA538477
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Beskrivelse

Mouse Monoclonal Antibody

This antibody has been tested in indirect ELISA.

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen APRIL
Applikationer Flow Cytometry, Western Blot
Klassifikation Monoclonal
Klon 2C2C11
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering PBS with 0.05% sodium azide
Gene TNFSF13
Genadgangsnr. O75888
Gene Alias 2310026N09Rik; A proliferation-inducing ligand; APRIL; CD256; TALL2; TALL-2; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; Tnfsf13; TNLG7B; Trdl1; TRDL-1; tumor necrosis factor (ligand) superfamily, member 13; tumor necrosis factor ligand 7B; tumor necrosis factor ligand superfamily member 13; tumor necrosis factor superfamily member 13; tumor necrosis factor-like protein ZTNF2; tumor necrosis factor-related death ligand-1; UNQ383/PRO715; ZTNF2
Gensymboler TNFSF13
Værtsarter Mouse
Immunogen Purified recombinant fragment of human CD256 (aa: 105-250) expressed in E. Coli.
Oprensningsmetode Protein G
Mængde 100 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 8741
Målarter Human
Indhold og opbevaring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttype Antibody
Form Liquid
Isotype IgG2b
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