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Tocris Bioscience™ Apoptosis Activator 2
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Artikelnummer. 18044832
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10 mg
50 mg
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Artikelnummer. Mængde
18044832 50 mg
18025102 10 mg
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Artikelnummer. 18044832 Leverandør Tocris Bioscience™ Leverandørnr. 2098/50

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Beskrivelse

Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis

Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 μM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 μM).
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 79183-19-0
Molekylær formel C15H9Cl2NO2

Tekniske data

Kemisk navn eller materiale Apoptosis Activator 2
Mængde 50 mg
Formel vægt 306.14
Renhed >99%
Molekylvægt (g/mol) 306.14
Produkttitel
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