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Tocris Bioscience™ AP C5
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Artikelnummer. 18768626
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18768626 10 mg
18767906 50 mg
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Artikelnummer. 18768626 Leverandør Tocris Bioscience™ Leverandørnr. 6626/10

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Beskrivelse

Potent and selective PKG2 inhibitor

AP C5 is a potent and selective protein kinase G type II (PKG2) inhibitor (pIC50 = 7.2). Displays >20-fold selectivity for PKG2 over PKG1 and PKA (pIC50 values are 4.6 and 4.8 for PKG1 and PKA, respectively). Blocks 8-pCPT-cGMP-dependent VASP phosphorylation in intestinal organoids. Also attenuates toxin-stimulated anion secretory responses in mouse intestinal tissue.
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Tekniske data

Kemisk navn eller materiale 4-[4-(1H-Imidazol-1-yl)phenyl]-N-2-propyn-1-yl-2-pyrimidinamine
CAS 2234272-10-5
Mængde 10 mg
Molekylær formel C16H13N5
Formel vægt 275.31
Renhed 98%
Produkttitel
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