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anti-TRADD Clone: 7G8, Invitrogen™
Beskrivelse
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
A16595 detects TRADD in Human samples. A16595 has been successfully used in WB and IP procedures. The immunogen for A16595 is synthetic peptide corresponding to residues surrounding glycine 227 of human TRADD.
Applications:
Immunoprecipitation, Western Blotting
Tekniske data
Tekniske data
| Antigen | TRADD |
| Klassifikation | Monoclonal |
| Klon | 7G8 |
| Konjugeret | Unconjugated |
| Genadgangsnr. | Q15628 |
| Værtsarter | Rabbit |
| Immunogen | synthetic peptide corresponding to residues surrounding glycine 227 of human TRADD. |
| Primær eller sekundær | Primary |
| Gen-id (Entrez) | 8717 |
| Målarter | Human |
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