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Phospho-CD142 (Ser290) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538458

Additional Details : Weight : 0.00900kg

Product Code. 15545381

  • 3510.00 DKK / 100µg
Estimated Shipment: 08-05-2024
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Description

Description

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.
Specifications

Specifications

Phospho-CD142 (Ser290)
Polyclonal
Unconjugated
F3
F3, Coagulation factor 3, TF, TFA, Coagulation Factor III
Rabbit
Antigen affinity chromatography
RUO
14066, 2152
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
P13726, P20352
F3
A synthetic phosphopeptide derived from human Coagulation Factor III around the phosphorylation site of Ser290 (E-N-SP-P-L)
100 μg
Primary
Human, Mouse
Antibody
IgG
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