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Phospho-CD142 (Ser290) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA538458
Additional Details : Weight : 0.00900kg
Description
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.Specifications
Phospho-CD142 (Ser290) | |
Polyclonal | |
Unconjugated | |
F3 | |
F3, Coagulation factor 3, TF, TFA, Coagulation Factor III | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
14066, 2152 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P13726, P20352 | |
F3 | |
A synthetic phosphopeptide derived from human Coagulation Factor III around the phosphorylation site of Ser290 (E-N-SP-P-L) | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |