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Paxillin Mouse, Unlabeled, Clone: 349, BD
Descrizione
A number of cytoskeletal proteins are tyrosine phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts. One of these is the 68 kDa paxillin protein. Paxillin is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers. It is also present in the focal adhesions of Madin-Darby canine kidney epithelial cells, but is absent from the cell adherens junctions of these cells. Paxillin purified from chicken gizzard migrates as a diffuse band on SDS-PAGE with molecular weight of 65-70 kDa. It binds to the rod domain of vinculin, another focal adhesion protein. It is thought that phosphorylation of paxillin may have a role in that disassembly of focal adhesions and stress fibers during transformation.
Specifica
Specifica
| Antigen | Paxillin |
| Applikationer | Western Blot |
| Klassifikation | Monoclonal |
| Klon | 349 |
| Koncentration | 1.0mg/mL |
| Konjugeret | Unconjugated |
| Formulering | Aqueous buffered solution containing glycerol and ≤0.09% sodium azide. |
| Værtsarter | Mouse |
| Immunogen | Chicken Paxillin aa. 1 to 557 |
| Oprensningsmetode | Affinity Purified |
| Vedi altri risultati |
For Research Use Only.
Titolo del prodotto
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