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Paxillin Mouse, Unlabeled, Clone: 349, BD

Artikelnummer. 15845229
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Mængde:
150 μg
50 μg
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Artikelnummer. Mængde
15845229 50 μg
15855229 150 μg
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Artikelnummer. 15845229 Leverandør BD Biosciences Leverandørnr. 610051

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Beskrivelse

Mouse Monoclonal Antibody

A number of cytoskeletal proteins are tyrosine phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts. One of these is the 68 kDa paxillin protein. Paxillin is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers. It is also present in the focal adhesions of Madin-Darby canine kidney epithelial cells, but is absent from the cell adherens junctions of these cells. Paxillin purified from chicken gizzard migrates as a diffuse band on SDS-PAGE with molecular weight of 65-70 kDa. It binds to the rod domain of vinculin, another focal adhesion protein. It is thought that phosphorylation of paxillin may have a role in that disassembly of focal adhesions and stress fibers during transformation.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Paxillin
Applikationer Western Blot
Klassifikation Monoclonal
Klon 349
Koncentration 1.0mg/mL
Konjugeret Unconjugated
Formulering Aqueous buffered solution containing glycerol and ≤0.09% sodium azide.
Værtsarter Mouse
Immunogen Chicken Paxillin aa. 1 to 557
Oprensningsmetode Affinity Purified
Mængde 50 μg
Regulatorisk status RUO
Forskningsdisciplin Cell Biology
Primær eller sekundær Primary
Målarter Canine, Chicken, Human, Mouse, Rat
Indhold og opbevaring Store undiluted at -20°C.
Isotype IgG1
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For Research Use Only.

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