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Indeholder: Rabbit affinity purified polyclonal anti-NUDT1 (100μg); Mouse monoclonal anti-NUDT1, IgG2aκ (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.
Beskrivelse
Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described.
ELISA
Tekniske data
| NUDT1 | |
| Monoclonal/Polyclonal | |
| This antibody pair set comes with matched antibody pair to detect and quantify protein level of human NUDT1. | |
| MTH1 | |
| Mouse, Rabbit | |
| 1 Set | |
| Stem Cell Biology | |
| 4521 | |
| Human | |
| IgG2a |
| ELISA | |
| Unconjugated | |
| NUDT1 | |
| NUDT1 | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-NUDT1 (100 μg) 2. Detection antibody: mouse monoclonal anti-NUDT1, IgG2a Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols. | |
| Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use. |
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