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Invitrogen™ NEFH Monoclonal Antibody (RMdO-20)

Artikelnummer. 10726653
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Mængde:
200 μg
Pakningsstørrelse:
Hver
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10726653 200 μg Hver
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Artikelnummer. 10726653 Leverandør Invitrogen™ Leverandørnr. 131300

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Beskrivelse

Mouse Monoclonal Antibody

This antibody reacts with 200 kDa subunit protein of human neurofilament. It specifically recognizes a nonphosphorylated epitope in the tail domain of NF-H. Dephosphorylation of NF-H will increase immunoreactivity with this antibody. This antibody is suitable for immunohistochemical staining of Bouin's and alcohol-fixed paraffin-embedded or frozen tissue sections. To stain, incubate 30-60 minutes at room temperature or overnight at 4°C.

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen NEFH
Applikationer ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Klassifikation Monoclonal
Klon RMdO-20
Koncentration 0.5 mg/mL
Konjugeret Unconjugated
Formulering PBS with 0.1% sodium azide
Gene Nefh
Genadgangsnr. P12036, P16884, P19246
Gene Alias 200 kDa neurofilament protein; CMT2CC; heavy neurofilament protein; I79_012512; intermediate filament protein; KIAA0845; LOW QUALITY PROTEIN: neurofilament heavy polypeptide; mKIAA0845; NEF3; Nefh; nefh.L; neurofilament; neurofilament 200kDa; neurofilament heavy; neurofilament heavy L homeolog; neurofilament heavy polypeptide; neurofilament heavy polypeptide-like; neurofilament triplet H protein; neurofilament, heavy polypeptide; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide L homeolog; neurofilament-H; NF 200 kD; NF200; Nfh; NF-H; NHC; XELAEV_18007418mg
Gensymboler Nefh
Værtsarter Mouse
Immunogen Adult Rat neurofilaments.
Oprensningsmetode Purified
Mængde 200 μg
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 100357177, 100753127, 101838568, 24587, 380684, 4744, 528842
Målarter Human, Mouse, Rat, Rabbit, Bovine, Hamster, Mollusca
Indhold og opbevaring -20°C
Produkttype Antibody
Form Liquid
Isotype IgG1 κ
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