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Invitrogen™ MKP4 Polyclonal Antibody
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Artikelnummer. 13483077
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Mængde:
100 μL
Pakningsstørrelse:
100µL
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13483077 100 μL 100µL
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Artikelnummer. 13483077 Leverandør Invitrogen™ Leverandørnr. PA528961

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Rabbit Polyclonal Antibody

Recommended positive controls: A431. Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X and MKP-4.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen MKP4
Applikationer Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Klassifikation Polyclonal
Koncentration 1 mg/mL
Konjugeret Unconjugated
Formulering 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene DUSP9
Genadgangsnr. Q99956
Gene Alias dual specificity phosphatase 9; dual specificity protein phosphatase 9; dual-specificity MAP kinase phosphatase 4; Dusp4; DUSP9; MAP kinase phosphatase 4; mitogen-activated protein kinase phosphatase 4; MKP4; MKP-4; Mpk4; Pyst3; serine/threonine specific protein phosphatase
Gensymboler DUSP9
Værtsarter Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MKP4. The exact sequence is proprietary.
Oprensningsmetode Antigen affinity chromatography
Mængde 100 μL
Regulatorisk status RUO
Primær eller sekundær Primary
Gen-id (Entrez) 1852
Målarter Human
Indhold og opbevaring Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttype Antibody
Form Liquid
Isotype IgG
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