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Invitrogen™ MKP4 Polyclonal Antibody

Beskrivelse
Recommended positive controls: A431. Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X and MKP-4.
Tekniske data
Tekniske data
| Antigen | MKP4 |
| Applikationer | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Klassifikation | Polyclonal |
| Koncentration | 1 mg/mL |
| Konjugeret | Unconjugated |
| Formulering | 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 |
| Gene | DUSP9 |
| Genadgangsnr. | Q99956 |
| Gene Alias | dual specificity phosphatase 9; dual specificity protein phosphatase 9; dual-specificity MAP kinase phosphatase 4; Dusp4; DUSP9; MAP kinase phosphatase 4; mitogen-activated protein kinase phosphatase 4; MKP4; MKP-4; Mpk4; Pyst3; serine/threonine specific protein phosphatase |
| Gensymboler | DUSP9 |
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Produkttitel
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