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Fibronectin Mouse, Unlabeled, Clone: 10, BD

Artikelnummer. 15815249
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Mængde:
150 μg
50 μg
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Artikelnummer. Mængde
15815249 150 μg
15805249 50 μg
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Artikelnummer. 15815249 Leverandør BD Biosciences Leverandørnr. 610078

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Beskrivelse

Mouse Monoclonal Antibody

The 240kDa dimeric fibronectin protein exists in two forms: a soluble protomer in body fluids and an insoluble multimer in the extracellular matrix. The latter is the primary functional form and creates a substrate for cell migration, a role which makes fibronectin vital to embryogenesis and wound response. Fibronectin mediates cytoskeletal organization, cell attachment, and cellular signaling through interactions with cellular receptors. Although various isoforms of fibronectin are derived by alternative splicing, they share a common N-terminus which is a critical region for cell surface binding in an initial step of multimer assembly. Further polymerization steps are regulated by fibronectin/integrin interactions and result in generation of the complex fibrils that constitute the fibronectin matrix.

Host Species: Mouse
Clone: 10
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human Fibronectin
Formula Weight [Chemical]: 240kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Tekniske data

Antigen Fibronectin
Applikationer Flow Cytometry
Klassifikation Monoclonal
Klon 10
Koncentration 250μg/mL
Konjugeret Unconjugated
Oversigt FN; LETS
Formulering Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Værtsarter Mouse
Immunogen Human Fibronectin
Oprensningsmetode Affinity Purified
Mængde 150 μg
Regulatorisk status RUO
Forskningsdisciplin Cell Biology
Primær eller sekundær Primary
Målarter Bovine, Canine, Chicken, Human, Mouse, Rat
Indhold og opbevaring Store undiluted at -20°C.
Isotype IgG1 κ
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For Research Use Only.

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