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CD80 Mouse anti-Human, PE, Clone: L307.4, BD

Artikelnummer. 15868858
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Mængde:
100 Tests
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Artikelnummer. Mængde
15868858 100 Tests
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Artikelnummer. 15868858 Leverandør BD Biosciences Leverandørnr. 557227

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Beskrivelse

Mouse Monoclonal Antibody

Reacts with B7/BB1, a 60kDa transmembrane glycoprotein which was clustered as CD80 in the Fifth International Workshop on Human Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on activated B cells, macrophages, and dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80 is also expressed on activated CD4+ and CD8+ T cells, appearing late after activation suggesting that activated T cells may be capable of autocrine costimulation via the CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell activation and a signal for IL-2 production.

TRUSTED_SUSTAINABILITY

Tekniske data

Antigen CD80
Applikationer Flow Cytometry
Klassifikation Monoclonal
Klon L307.4
Konjugeret PE
Oversigt B7.1; B7-1; Activation B7-1 antigen; B7; BB1; CD28LG; CD28LG1; LAB7
Formulering Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Værtsarter Mouse
Immunogen Human B7-transfected L cells
Oprensningsmetode Affinity Purified
Mængde 100 Tests
Regulatorisk status RUO
Forskningsdisciplin Immunology
Primær eller sekundær Primary
Målarter Human
Indhold og opbevaring Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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